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A synthetic version of a peptide naturally found in human cells could potentially enhance dental care and treatment, it has been suggested.
Researchers at RegenRx have announced that the peptide, known as TI4, has completed an initial phase of clinical trials.
During these trials, TI4 was found to provide protection to human gum cells. In related studies, it also provided multifunctional protection to cells in the eye and heart.
"Because of its multifunctional role in protecting cells against damage, TI4 may have significant potential for use as an oral healthcare aid," commented Dr Gabriel Sosne, associate professor of ophthalmology at Wayne State University School of Medicine.
It works by suppressing the secretion of inflammatory cells, protecting gum cells against toxic agents and preventing gum cells from undergoing apoptosis.
Sonse attributed the peptide's efficacy to its "anti-microbial, anti-inflammatory, anti-apoptotic and cyto-protective properties."
Previously, studies at the National Institutes of Health have suggested that TI4 could be effective in speeding up the healing of wounds and protecting tissues.
The latest findings are published in the European Journal of Oral Sciences.
© 2008 Brafton Inc.
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