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Ovarian cancer linked to missing teeth
Updated: 2/29/2008 12:07:10 PM

Women with ovarian cancer could have a higher risk for losing teeth or abnormally small teeth according to a new study.

Researchers form the University of Kentucky, Lexington found that 20 in 100 ovarian cancer patients had a condition called hypodontia, which is where one or more adult teeth never form under the gums or formed teeth are unusually small or peg-shaped.

Overall, the researchers found that about 20 in 100 ovarian cancer patients had a family history of hypodontia with only about two in 100 healthy women without a history of the condition diagnosed with hypodontia.

Alterations in certain genes was thought to possibly affect tooth developments and ovarian cancer risk. A previous study in 2004 suggested that a mutation in a gene called AXIN2 could cause hypodontia and colon cancer.

Though hypdontia occurs in just three to 12 percent of the population, it is more common in women, while ovarian cancer is difficult to diagnose in its earliest stages, when it is most curable.

The study has been published in the February issue of the Journal of the American Dental Association.

ADNFCR-1507-ID-18490376-ADNFCR

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